[5-(Trifluoromethyl)pyridin-2-yl]methanol - Names and Identifiers
[5-(Trifluoromethyl)pyridin-2-yl]methanol - Physico-chemical Properties
Molecular Formula | C7H6F3NO
|
Molar Mass | 177.12 |
Density | 1.362±0.06 g/cm3(Predicted) |
Boling Point | 215.5±35.0 °C(Predicted) |
Flash Point | 84.1°C |
Vapor Presure | 0.0862mmHg at 25°C |
pKa | 13.16±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Irritant |
Refractive Index | 1.462 |
MDL | MFCD04117762 |
[5-(Trifluoromethyl)pyridin-2-yl]methanol - Risk and Safety
[5-(Trifluoromethyl)pyridin-2-yl]methanol - Introduction
[5-(Trifluoromethyl)pyridin-2-yl]methanol is an organic compound with the chemical formula C7H5F3NO. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: White or off-white solid
-Solubility: Soluble in organic solvents such as ether, methanol and dichloromethane
-Melting point: About 100-101 ° C
-Boiling point: About 238-239 ° C
-Density: 1.376g/cm³
Use:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol is a commonly used organic synthesis intermediate, which is widely used in the fields of medicine, pesticide and chemical industry.
-It is often used as a reagent and catalyst in organic synthesis reactions, especially in fluorination reactions.
-The compound can also be used to prepare other organic compounds, such as drugs and pesticides that use it as derivatives.
Method:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol can be prepared by the following reaction: 5-trifluoromethylpyridine and methanol are reacted under appropriate reaction conditions to obtain the target product.
Safety Information:
- [5-(Trifluoromethyl)pyridin-2-yl]methanol is generally relatively safe under the correct use and storage, but the following matters still need to be paid attention:
-This compound can cause eye and skin irritation and direct contact should be avoided.
-Avoid contact with oxidants during operation or storage to prevent fire or explosion.
-During use, good ventilation measures should be taken to avoid inhalation of aerosols.
-Correct laboratory procedures and safe handling should be followed when handling the compound.
Last Update:2024-04-09 02:00:45